Which one of the following facilitates transfer of bulk data from hard disk to main memory with the highest throughput?

$$ * \,\,\,\,\,\,\,\,\,\,\,$$ Interrupt from $$CPU$$ temperature sensor (raises interrupt if $$CPU$$
$$\,\,\,\,\,\,\,\,\,\,\,\,\,\,$$ temperature is too high)
$$ * \,\,\,\,\,\,\,\,\,\,\,$$ Interrupt from Mouse (raises interrupt if the mouse is moved or a button is
$$\,\,\,\,\,\,\,\,\,\,\,\,\,\,\,$$pressed)
$$ * \,\,\,\,\,\,\,\,\,\,\,$$ Interrupt from Keyboard (raises interrupt when a key is pressed or released)
$$ * \,\,\,\,\,\,\,\,\,\,\,$$ Interrupt from Hard Disk (raises interrupt when a disk read is completed)

Which one of these will be handled at the $$HIGHEST$$ priority?