The following pedigree diagram shows the inheritance of a rare genetic disorder (filled shapes depict affected individuals). Which of the following is the most likely pattern of inheritance of the disorder?

In an island with 10,000 individuals, four have sickle cell anemia, a recessive autosomal disease. Assuming that the locus is in Hardy-Weinberg equilibrium, how many individuals in that island are expected to be heterozygous for the disease allele?

The following pedigree chart shows the inheritance of a genetic disorder. I-2 and III-2 are the only affected individuals. Which one of the following is the correct pattern of inheritance of the disorder, and the genotype of the II- 3 individual?

In a given species of flowering plant, the colour of the seeds is exclusively determined by the colour of its seed coat. Seed coat colour in this species is governed by a nuclear gene with two alleles. The WHITE ( $W$ ) allele is dominant over brown ( $w$ ) allele. If a plant with brown seeds $(w w)$ is crossed as a female with pollen from a white seed $(W W)$ plant, what will be the seed colour and the genotype of the embryo in the resultant seeds obtained from this cross?

A single point mutation in gene ' $X$ ' results in breathing difficulty, hypertension as well as partial sterility. Which among the following best explains the observed phenotypes?

In a cross between individuals of the genotypes PpQQRrSS and ppqqRrSS, what will be the expected number of progenies with the genotype ppQQRrSS in a population of 400 individuals, assuming independent assortment?

Nine percent of a population cannot taste a certain food item because of a recessive allele of the gene IAT. Assuming the population is in Hardy-Weinberg equilibrium, what will be the frequency of dominant and recessive alleles, respectively?

A hypothetical plant species shows two flower colour phenotypes- red and white. Red is dominant over white. In a population, this flower colour locus was found to be in HardyWeinberg equilibrium. If 490 out of a total population size of 1000 plants were found to be white-flowered, how many of the red-flowered plants will be heterozygous?